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http://natural-sciences.nwu.ac.za/physical-and-chemical-sciences/physical-and-chemical-sciences1

Physical and Chemical Sciences_1


 

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http://natural-sciences.nwu.ac.za/mitochondrial-laboratory/contact-mitochondrial-research-laboratory

Contact the Mitochondrial Research Laboratory

Postal Address:   Private Bag X 6001 Potchefstroom 2520   South Africa Physical Address:   Mitochondria Research Laboratory  Building F3 – Biochemistry  …

 

http://natural-sciences.nwu.ac.za/mitochondria-research-laboratory/active-researchers

Active Researchers

Dr Maryke Schoonen Laboratory Manager Orcid   Dr Karin Terburgh Postdoctoral Fellow Orcid    Dr Tendai Makwikwi Postdoctoral Fellow Orcid   Dr Roksana Majewska PhD Student Orcid…

 

http://natural-sciences.nwu.ac.za/mitochondria-research-laboratory/funders

Funders

                           

 

http://natural-sciences.nwu.ac.za/mitochondria-research-laboratory/collaborators

Collaborators

National: Prof Izelle Smuts & Dr Kealeboga Rammego, Department of Paediatrics & Steve Biko Akademic Hospital, University of Pretoria; Prof Jo Wilmshurst, Mrs Surita Meldau, Dr Gill Riordan, Department of Paediatric Neurology, Red Cross War Memorial Children’s Hospital, and NHLS Laboratory at the University of Cape Town…

 

http://natural-sciences.nwu.ac.za/mitochondria-research-laboratory/history-research-group

History of the Research Group

The group was formed in 2001 with the aim of forming a specialist research group to study and provide biochemical diagnostic capacity for mitochondrial- and other inherited metabolic diseases in South Africa.  Over two decades this research aim expanded in scope to now include a wide range of investigations in several types of disease…

 

http://natural-sciences.nwu.ac.za/mitochondria-research-laboratory/background-research

Background to the Research

With the background and expertise of the division of Biochemistry in inherited metabolic diseases and metabolism, the research topics of the group are structured around the involvement of the mitochondrial oxidative phosphorylation (OXPHOS) system in human diseases. Defects in the mitochondrial energy metabolism is not only the largest group of…

 

http://natural-sciences.nwu.ac.za/mitochondrial-laboratory/research-objectives-and-technologies-used

Research Objectives and Technologies Used

The MRL is set up to investigate various aspects of mitochondrial function and disease from different approaches and is therefore a truly multidisciplinary research group.  The laboratory is a very well-equipped with specialised apparatus for the following: Mitochondrial function: Mitochondrial…

 

http://natural-sciences.nwu.ac.za/mitochondrial-laboratory/current-research-activities-and-developments

Current Research Activities and Developments

The current projects of the MRL fall into three groups:   Mitochondrial disorders in the SA population: molecular genetics and metabolomics Cohort investigations with national and international researchers and clinicians   Adaptive responses in…

 

http://natural-sciences.nwu.ac.za/mitochondrial-laboratory/publications

Publications

Our publications are listed in order of the most relevant over the last five years:   Reinecke CJ, Koekemoer G, van der Westhuizen FH, Louw R, Lindeque JZ, Mienie LJ, Smuts I. 2012. Metabolomics of urinary organic acids in respiratory chain deficiencies. Metabolomics 8, 264-283 (IF 4.505). van der Walt EM…

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